RecombinantBiotinylatedHumanMSLN/MesothelinProtein,hFc-AviTag分子别名(Synonyms)Mesothelin;CAK1;MSLN;MPFSMRP表达区间及表达系统(Source)BiotinylatedHumanMSLN/MesothelinProteinisexpressedfromHEK293withhFctagandAvitagattheC-Terminus.ItcontainsGlu296-Gly580.[Accession|Q13421-2]分子量大小(MolecularWeight)TheproteinhasapredictedMWof61.1kDa.Duetoglycosylation,theproteinmigratesto70-80kDabasedonSDS-PAGEresult.(Endotoxin)Lessthan1EUperμgbytheLALmethod.纯度(Purity)>95%asdeterminedbySDS-PAGEandHPLC.活性(Activity)ELISAData:ImmobilizedAnti-MSLNAntibody,hFcTagat1μg/ml(100μl/well)ontheplate.DoseresponsecurveforBiotinylatedHumanMSLN,hFcTagwiththeEC50of18.4ng/mldeterminedbyELISA.常用的跨膜蛋白表达系统包括大肠杆菌表达系统、酵母表达系统、昆虫细胞表达系统和哺乳动物细胞表达系统等。Recombinant Biotinylated Human TIGIT Protein,His-Avi Tag

RecombinantBiotinylatedCynomolgusSiglec-10Protein,His-AviTag性能参数分子别名(Synonyms)SLG2;SIGLEC10;MGC126774;PRO940表达区间及表达系统(Source)BiotinylatedCynomolgusSiglec-10ProteinisexpressedfromHEK293withHistagandAvitagattheC-terminus.ItcontainsThr17-Asn552.[Accession|A0A2K5WBX8]分子量大小(MolecularWeight)TheproteinhasapredictedMWof61.71kDa.Duetoglycosylation,theproteinmigratesto72-82kDabasedonSDS-PAGEresult.(Endotoxin)Lessthan1EUperμgbytheLALmethod.纯度(Purity)>95%asdeterminedbySDS-PAGE制剂(Formulation)Suppliedas0.22μmfilteredsolutionin25mMMES,150mMNaCl,0.5MArginine(pH5.0).储存条件Theproductshouldbestoredat-85~-65℃for1yearfromdateofreceipt.Recommendtoaliquottheproteinintosmallerquantitieswhenfirstusedandavoidrepeatedfreeze-thawcycles.Rat FGF-9 Protein全长跨膜蛋白CB1,即受体1(Cannabinoid Receptor 1),是一种G蛋白偶联受体(GPCR)。

胶原蛋白是哺乳动物体内含量多的功能性蛋白[1]。胶原蛋白由3条α链的多肽链亚基组成,α链自身构型为左手螺旋,三条α链又互相缠绕成右手螺旋结构,即胶原蛋白的“胶原域”[2]。胶原蛋白的一级结构分析结果显示,其肽链由(Gly-X-Y)n组成,其中X通常是脯氨酸,Y通常是羟脯氨酸[3]。按照胶原蛋白发现的先后顺序,可将其分为Ⅰ型、Ⅱ型、Ⅲ型等28种胶原蛋白[4],Ⅰ型胶原蛋白分子组成为[α1(Ⅰ)]2α2(Ⅰ),主要分布于骨骼中[5];Ⅱ型胶原蛋白由[α1(Ⅱ)]3组成,主要由软骨细胞产生,因其含有大量赖氨酸残基,因而糖基化率较高[6];Ⅲ型胶原蛋白分子组成为[α1(Ⅲ)]3,因含半胱氨酸所以肽链间形成二硫键,因此其本身就可形成细纤维,Ⅲ型胶原蛋白血管中含量较高,主要存在于肺泡间质中且分布杂乱,因而形成复杂的网状结构,正是这种结构使得肺组织具有良好的柔韧性与弹性,并且可以为细胞提供充足养分,使得皮肤饱满透亮[7]。
Name:AITRL,MouseSynonyms:Activation-inducedTNFRmemberLigand,TNFSF18,GITRL,TL-6Description:Activation-InducibleTNF-RelatedLigand(AITRL),alsoknownasGlucocorticoid-InducedTNF-RelatedLigand(GITRL),belongstothetumornecrosisfactorsuperfamily(TNFSF).AITRLisaTypeIIsingletransmembraneproteinandshareslowconservationwithintheextracellulardomainwithotherTNFSFmembers.AITRLisexpressedonmacrophages,immatureandmaturedendriticcellsandBcells.Itsreceptor,Activation-InducibleTNFRfamilyReceptor(AITR),isexpressedonTlymphocytes,naturalkiller(NK)cells,andantigen-presentingcells.AfterbindingbyAITRL,AITRcanbereleased.AITRactivationincreasesresistancetotumorsandviralinfectionsandisinvolvedinautoimmuneandinflammatoryprocesses.Inaddition,activatedAITRincreasesTCR-inducedTcellproliferationandcytokineproductionandrescuesTcellsandNKcellsfromapoptosis.RecombinantmouseActivation-InducibleTNF-RelatedLigand(rmAITRL)producedinE.在蛋白质的晶体学研究中,去除糖链可以帮助获得去糖基化的蛋白质,这有助于更清晰地解析蛋白质的三维结构。

透明质酸酶活力单位(Unitdefinition)基于USP透明质酸酶参照标准,即每分钟在37℃,pH5.7的2mL反应液中引起OD6000.330个变化定义为一个活力单位。抑制剂(Inhibitor)Fe2+,Fe3+,Zn2+,Cu2+,肝素,金精三羧酸,硫酸,硝酸,乙酰化透明质酸,硫酸纤维素酯,胆汁等结构式(Structure)运输和保存方法冰袋运输。-20℃保存,两年有效。溶液配制溶于0.02MPBS(pH7.0),含77mMNaCl和0.01%BSA,浓度为1mg/mL。现配现用。该产品储存液不稳定,使用时建议现配现用。为了您的安全和健康,请穿实验服并戴一次性手套操作。肠激酶作为研究工具,用于探索蛋白质结构-功能关系,以及在蛋白质工程中进行蛋白质的定点突变。Recombinant Human TRAIL R1/DR4/TNFRSF10A Protein,His-Avi Tag
泛素-蛋白酶体途径在调控多种细胞过程中的关键作用,靶向这一途径的药物开发已成为预防某些疾病的新策略。Recombinant Biotinylated Human TIGIT Protein,His-Avi Tag
AngiotensinIConvertingEnzyme(ACE-2),alsocalledACEH(ACEhomologue),isadimeric,zinc-dependentmetalloproteaseoftheACEfamilythatalsoincludessomaticandgerminalACE.ACE-2mRNAisfoundathighlevelsinheart,testis,andkidneyandatlowerlevelsinawidevarietyoftissues.ACE-2istheSARS-CoVandSARS-CoV2Spikeproteinreceptorinvivo,functionscatalyticallyasacarboxypeptidasetocleaveseveralsubstratesincludingangiotensinsIandII,andactsasapartnerforB0AT1-familyaminoacidtransporters.Throughthesefunctions,ACE-2hasbeenshowntobeinvolvedinseveraldiseasesincludingSARS,COVID19,acutelunginjury,heartdisease,liverandlungfibrosis,inflammatorylungdisease,andcardiopulmonarydisease.FulllengthACE-2proteinincludesanextracellularregioncomposedofasingleN-terminalpeptidasedomainandC-terminalcollectrin-likedomain(CLD),atransmembranedomain,andashortcytoplasmictail.TheN-terminalpeptidaseregionisrequiredforbindingtoSARS-CoVandSARS-CoV2spikeproteins,whiletheCLDcontainsaregionthatpromotesdimerizationandassociationwithaminoacidtransporters.Recombinant Biotinylated Human TIGIT Protein,His-Avi Tag
SYBRGreenqPCRMix(2×,LowROX)是一种为实时荧光定量PCR(qPCR)设计的即用型预混液,适用于需要低浓度ROX校正染料的qPCR仪器。该产品结合了SYBRGreenI荧光染料和优化的反应体系,能够实现有效、特异的基因定量检测。产品特点有效热启动酶:采用化学修饰的TaqDNA聚合酶,结合抗体或化学修饰技术,有效抑制低温下的非特异性扩增,提高反应的特异性和灵敏度。优化的反应体系:包含优化的qPCRBuffer、dNTPs、SYBRGreenI荧光染料和低浓度ROX,适用于多种qPCR仪器。低浓度ROX:适用于需要低浓度ROX作为校正染料的qPCR仪器,如ABI7500、Vi...